How Polyethylene Glycol (PEG) in Vaccines May Cause Allergic Reactions

How Polyethylene Glycol (PEG) in Vaccines May Cause Allergic Reactions

PEG is an important part of the lipid nanoparticles based vaccines. Moderna COVID vaccine mRNA-1273 and Pfizer-BionTech COVID vaccine BNT162b2 contain PEG2000 in abundance. Let’s review why some people are getting allergic reactions with these vaccines, and the impact on the patient’s immune system for the future PEGylated therapies. Direct Link to Dr. Mobeen Syeed on Odysee

Lipidnanoparticle Based Vaccines and Allergic Reactions (Frontline Covid-19 Critical Care Alliance)

During this COCA call, clinicians will give an overview of recommendations for use of COVID-19 vaccines in certain populations. Clinicians will learn more about the recent reports of anaphylaxis following vaccination, as well as CDC’s updated clinical considerations around contraindications and precautions to vaccination.

This video can also be viewed at https://emergency.cdc.gov/coca/wmv/2020/12_30_2020_coca_call.mp4

Humans commonly have low level antibodies to poly(ethylene) glycol (PEG) due to environmental exposure. (PEG is a lipid nanoparticle) https://pubs.acs.org/doi/10.1021/acsnano.2c04543

Inhalable hybrid nanocarriers for respiratory disorders

PEGylated nanoparticles possess a longer circulation half-life because they escape capture and phagocytosis by various organs. PEGylated lipid nanoparticles are prepared by adding PEG esters in the lipid phase. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/pegylated-lipid

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